Publicaciones
   
2010

A Alcina, Ó Fernández, JR Gonzalez, A Catalá-Rabasa, M Fedetz, DNdagire, L Leyva, M Guerrero, C Arnal, C Delgado, M Lucas, G Izquierdo and F Matesanz Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis. European Journal of Human Genetics 2010, 18, 827-831

A Alcina, K Vandenbroeck, D Otaegui, A Saiz, J R Gonzalez, O Fernandez, M L Cavanillas, M C Cénit, R Arroyo, I Alloza, M García-Barcina, A Antigüedad, L Leyva, G Izquierdo, M Lucas, M Fedetz, M J Pinto-Medel, J Olascoaga, Y Blanco, M Comabella, X Montalban, E Urcelay and F Matesanz. The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis. Genes and Immunity 2010, 11, 439-445.

 
2009  

Up-regulation of placental leptin by human chorionic gonadotropin.
Maymó JL, Pérez Pérez A, Sánchez-Margalet V, Dueñas JL, Calvo JC, Varone CL.
Endocrinology. 2009; 150(1):304-13.

Anti-U3 RNP autoantibodies in systemic sclerosis.
Aggarwal R, Lucas M, Fertig N, Oddis CV, Medsger TA Jr.
Arthritis Rheum. 2009; 60(4):1112-8.

C cells evolve at the same rhythm as follicular cells when thyroidal status changes in rats.
Martín-Lacave I, Borrero MJ, Utrilla JC, Fernández-Santos JM, de Miguel M, Morillo J, Guerrero JM, García-Marín R, Conde E.
J Anat. 2009; 214(3):301-9.

What are the biochemical parameters of pleural fluid that best identify parapneumonic effusions?
Santotoribio JD, León-Justel A, Delgado-Pecellín C, Guerrero JM.
Ann Clin Biochem. 2009; 46(Pt 2):176-7.

A novel interplay between membrane and nuclear melatonin receptors in human lymphocytes: significance in IL-2 production.
Lardone PJ, Carrillo-Vico A, Molinero P, Rubio A, Guerrero JM.
Cell Mol Life Sci. 2009 ;66(3):516-25.

Melatonin present in beer contributes to increase the levels of melatonin and antioxidant capacity of the human serum.
Maldonado MD, Moreno H, Calvo JR.
Clin Nutr. 2009; 28(2):188-91.

The role of melatonin in the immuno-neuro-psychology of mental disorders.
Maldonado MD, Pérez-San-Gregorio MA, Reiter RJ.
Recent Pat CNS Drug Discov. 2009;4(1):61-9.

Donor-specific antibodies against HLA, MICA, and GSTT1 in patients with allograft rejection and C4d deposition in renal biopsies.
Alvarez-Márquez A, Aguilera I, Gentil MA, Caro JL, Bernal G, Fernández Alonso J, Acevedo MJ, Cabello V, Wichmann I, Gonzalez-Escribano MF, Núñez-Roldán A.
Transplantation. 2009 15;87(1):94-9

Toll-like receptor stimulation differentially regulates vasoactive intestinal peptide type 2 receptor in macrophages.
Herrera JL, Gonzalez-Rey E, Fernandez-Montesinos R, Quintana FJ, Najmanovich R, Pozo D.
J Cell Mol Med. 2009; 13, 1-9.

Alcina A, Fedetz M, Ndagire D, Fernández O, Leyva L, Guerrero M, Abad-Grau MM, Arnal C, Delgado C, Lucas M, Izquierdo G, Matesanz F.  IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D). PLoS ONE. 2009;4(1):e4137.

M Farez, FJ Quintana, AH Iglesias, CF Lucchinetti, G Izquierdo, M Lucas and HL Weiner. Activation of poly-ADP polymerase by 15-oxysterols in neuroinflammation.  Nature Immunology 2009, 10, 958-964.

2008

Leptin prevents apoptosis of trophoblastic cells by activation of MAPK pathway.
Pérez-Pérez A, Maymó J, Dueñas JL, Goberna R, Calvo JC, Varone C, Sánchez-Margalet V.
Arch Biochem Biophys. 2008 ; 477(2): 390-5.

Profile of patients triply infected with HIV and the hepatitis B and C viruses in the HAART era.
Maida I, Ríos MJ, Pérez-Saleme L, Ramos B, Soriano V, Pegram PS, Mura MS, Sánchez-Margalet V, Saldívar-Cornejo I, Wilkin A, Babudieri S, Núñez M.
AIDS Res Hum Retroviruses. 2008; 24(5):679-83.

Leptin promotes cell survival and activates Jurkat T lymphocytes by stimulation of mitogen-activated protein kinase.
Fernández-Riejos P, Goberna R, Sánchez-Margalet V.
Clin Exp Immunol. 2008; 151(3):505-18.
Glucose-6-phosphate dehydrogenase activity in Parkinson's disease.
Gao L, Mir P, Díaz-Corrales FJ, Mejías R, Carrillo F, Vime PJ, Díaz-Martín J, Palomino A, Carballo M, Pintado E, Lucas M, López-Barneo J.
J Neurol. 2008; 255(11):1850-1.

May anomalous X chromosome methylation be responsible for the spontaneous abortion of a male foetus?
Martínez R, Bonilla-Henao V, Ramos I, Sobrino F, Lucas M, Pintado E.
J Genet. 2008; 87(3):261-4.

Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis.
Quintana FJ, Farez MF, Viglietta V, Iglesias AH, Merbl Y, Izquierdo G, Lucas M, Basso AS, Khoury SJ, Lucchinetti CF, Cohen IR, Weiner HL.
Proc Natl Acad Sci U S A. 2008; 105(48):18889-94.

Highly skewed inactivation of the wild-type X-chromosome in asymptomatic female carriers of spinal and bulbar muscular atrophy (Kennedy's disease).
Paradas C, Solano F, Carrillo F, Fernández C, Bautista J, Pintado E, Lucas M.
J Neurol. 2008; 255(6):853-7.

The high producer variant of the Fc-receptor like-3 (FCRL3) gene is involved in protection against multiple sclerosis.
Matesanz F, Fernández O, Milne RL, Fedetz M, Leyva L, Guerrero M, Delgado C, Lucas M, Izquierdo G, Alcina A.
J Neuroimmunol. 2008; 195: 146-50.

Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations.
Kristjansdottir G, Sandling JK, Bonetti A, Roos IM, Milani L, Wang C, Gustafsdottir SM, Sigurdsson S, Lundmark A, Tienari PJ, Koivisto K, Elovaara I, Pirttilä T, Reunanen M, Peltonen L, Saarela J, Hillert J, Olsson T, Landegren U, Alcina A, Fernández O, Leyva L, Guerrero M, Lucas M, Izquierdo G, Matesanz F, Syvänen AC.
J Med Genet. 2008; 45(6):362-9.

Treatment with testosterone or estradiol in melatonin treated females and males MRL/MpJ-Faslpr mice induces negative effects in developing systemic lupus erythematosus.
Jimenez-Caliani AJ, Jimenez-Jorge S, Molinero P, Rubio A, Guerrero JM, Osuna C.
J Pineal Res. 2008; 45(2):204-11.

Driving neural stem cells towards a desired phenotype.
Reimers D, Gonzalo-Gobernado R, Herranz AS, Osuna C, Asensio MJ, Baena S, Rodríguez M, Bazán E.
Curr Stem Cell Res Ther. 2008; 3(4):247-53.

Melatonin usage in ulcerative colitis: a case report.
Maldonado MD, Calvo JR.
J Pineal Res. 2008; 45: 339-40.

PTPN22 C1858T polymorphism and the outcome of hepatitis C virus infection.
Montes-Cano MA, García-Lozano JR, Aguilar-Reina J, Romero-Gómez M, Barroso N, Nuñez-Roldán A, Martín J, González-Escribano MF.
Viral Immunol. 2008;21(4):491-4.

Clinical Relevance and Prevalence of Polymorphisms in CYP3A5 and MDR1 Genes That Encode Tacrolimus Biotransformation Enzymes in Liver Transplant Recipients.
Barrera-Pulido L, Aguilera-García I, Docobo-Pérez F, Alamo-Martínez JM, Pareja-Ciuró F, Nuñez-Roldán A, Gómez-Bravo MA, Bernardos-Rodríguez A.
Transplant Proc. 2008;40(9):2949-51.

Evaluation of third generation anti-CCP antibodies in the diagnosis of rheumatoid arthritis from undifferentiated polyarthritis after 4 years of follow-up.
Caro-Oleas JL, Fernández-Suárez A, Reneses Cesteros S, Porrino C, Núñez-Roldán A, Wichmann Schlipf I.
Clin Exp Rheumatol. 2008;26(3):461-3.

Positive association of anticytoskeletal endothelial cell antibodies and cardiac allograft rejection.
Alvarez-Márquez A, Aguilera I, Blanco RM, Pascual D, Encarnación-Carrizosa M, Alvarez-López MR, Wichmann I, Núñez-Roldán A.
Hum Immunol. 2008;69(3):143-8.

Anti-glutathione S-transferase T1 antibody-mediated rejection in C4d-positive renal allograft recipients.
Aguilera I, Alvarez-Marquez A, Gentil MA, Fernandez-Alonso J, Fijo J, Saez C, Wichmann I, Nuñez-Roldan A.
Nephrol Dial Transplant. 2008l;23(7):2393-8.

Tiopronin monolayer-protected silver nanoparticles modulate IL-6 secretion mediated by Toll-like receptor ligands.
Castillo PM, Herrera JL, Fernandez-Montesinos R, Caro C, Zaderenko AP, Mejías JA, Pozo D.
Nanomed. 2008;3(5):627-35.

Alzheimer's disease beyond the genomic era: nuclear magnetic resonance (NMR) spectroscopy-based metabolomics.
Barba I, Fernandez-Montesinos R, Garcia-Dorado D, Pozo D.
J Cell Mol Med. 2008; 12(5A):1477-85.

Immune-based disorders: the challenges for translational immunology.
Pozo D.
J Cell Mol Med. 2008;12(4):1085-6.

Heme oxygenase-1 expression is down-regulated by angiotensin II and under hypertension in human neutrophils.
Alba G, El Bekay R, Chacón P, Reyes ME, Ramos E, Oliván J, Jiménez J, López JM, Martín-Nieto J, Pintado E, Sobrino F.
J Leukoc Biol. 2008; 84(2):397-405.

Paradas C, Solano F, Carrillo F, Fernández C, Bautista J, Pintado E, Lucas M (2008). Skewed X Inactivation of the Normal Allele in Spino-Bulbar-Muscular Atrophy in female carriers. J Neurology 255:853-7.

Matesanz F, O Fernández, R Milne, M Fedetz, L Leyva, M Guerrero, C Delgado,   M Lucas, G Izquierdo, and Alcina A. (2008) The high producer variant of the Fc -Receptor Like-3 (FCRL3) gene is involved in protection against Multiple Sclerosis.
 J Neuroimmunology 195:146-50

Lin Gao, Pablo Mir, Francisco J. Díaz-Corrales, Rebeca Mejías, Fatima Carrillo, Pablo J. Vime, Juan Díaz-Martín, Alfredo Palomino, Manuel Carballo, Elizabeth Pintado, Miguel Lucas, José Lopez-Barneo (2008)Glucose-6-phosphate dehydrogenase activity in Parkinson’s disease

J Neurology 255: 1580-81

Kristjansdottir G, Sandling J, Sigurdsson S, Bonetti A, Roos I, Lundmark A, Tienari P, Hillert J, Olsson T, Alcina A, Fernández O, Leyva L, Guerrero M, Lucas M, Izquierdo G, Matesanz F, and Syvänen A-C (2008)

Polymorphisms in the interferon regulatory factor 5 (IRF5) gene are associated with multiple sclerosis in three distinct populations J Medical Genetics 45: 362-9.

Quintana FJ, Farez MF, Viglietta V, Iglesias AH, Merbl Y, Izquierdo G, Lucas M, Basso AS, Khoury SJ, Lucchinetti CF, Cohen IR, Weiner HL. (2008). Antigen microarrays identify unique serum autoantibody signatures associated with different clinical forms and pathologic subtypes of multiple sclerosis. Proc  Natl  Acad  Sci  U S A. 105:18889-94.

Martínez R, Bonilla-Henao V, Ramos I,  Sobrino F, Lucas M, Pintado E. May anomalous X chromosome methylation be responsible for the spontaneous abortion of a male foetus? (2008). J Genet. 87:261-4

 

2007
Lucas M, Suárez R, Marcos A, Solano F, Venegas A, García-Sánchez MI, Ortiz  L, Izquierdo G (2007). Arg113His mutation of vanishing white matter is not present in multiple sclerosis. Multiple Sclerosis 12: 1-4.

Ortiz L, Costa AF,  Bellido ML, Solano F, García-Moreno JM, Gamero MA, Izquierdo G, Chadli A, Falcao F, Ferro F, Salas J, Álvarez-Cermeño JC, Montori M, Ramos-Arroyo MA, Palomino A, Pintado E, Lucas M. (2007) Study of cerebral cavernous malformation in Spain and Portugal: High prevalence of a 14 bp deletion in exon 5 of MGC4607 (CCM2 gene). J Neurology, 254:322–326

 


  :: Departamento de Bioquímica Médica y Biología Molecular, Universidad de Sevilla. Avda. Sánchez Pizjuan, 4. 41009, Sevilla.